星科生物科技 -- SSBCWSM2
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SSBCWSM2

Inflammation is a defense mechanism of the biological tissues to damage factors. The damaged tissue cells will release histamine to stimulate surrounding vessels. That causes peripheral vascular dilatation and increase the blood flow of that part, resulting in red and hot symptoms, and microvascular permeability, plasma exudation mecrease which causes swelling and constricts the nerves to cause pain. Excessive inflammation or long-term chronic inflammation are harmful to the human body. It has been proven that many chronic diseases, including cancer, diabetes, cardiovascular disease, and Alzheimer’s disease, are correlated with chronic inflammation.

SSBCWSM2, the natural product has been extracted and purified from Taiwan endemic plants whose chemical structure were determined by spectral analysis (1D- and 2D-NMR, IR, UV, and MS). The R&D team of Starsci Biotech cooperated with academic institutes on using LPS to induce RAW264.7 cells to produce NO, and then conducted anti-inflammatory assay and tested the compounds. The results showed that SSBCWSM2 has significant effects on inhibiting the NO production activity and has no effect on cell viability. We furthered conducted mouse ears smear test and the results showed that the SSBCWSM2 compound has significant effects on inhibiting the inflammation and swelling of mouse ears. We are currently conducting other relevant immunological tests. The results are applying the patents.



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